Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies

Human pluripotent stem cells (PSCs), which are composed of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), provide an opportunity to advance cardiac cell therapy–based clinical trials. However, an important hurdle that must be overcome is the risk of teratoma formation after...

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Detalles Bibliográficos
Autores principales: Chour, Tony, Tian, Lei, Lau, Edward, Thomas, Dilip, Itzhaki, Ilanit, Malak, Olfat, Zhang, Joe Z., Qin, Xulei, Wardak, Mirwais, Liu, Yonggang, Chandy, Mark, Black, Katelyn E., Lam, Maggie P.Y., Neofytou, Evgenios, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119193/
https://www.ncbi.nlm.nih.gov/pubmed/33830086
http://dx.doi.org/10.1172/jci.insight.142000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119193/
https://www.ncbi.nlm.nih.gov/pubmed/33830086
http://dx.doi.org/10.1172/jci.insight.142000

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