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Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
Human pluripotent stem cells (PSCs), which are composed of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), provide an opportunity to advance cardiac cell therapy–based clinical trials. However, an important hurdle that must be overcome is the risk of teratoma formation after...
Autores principales: | Chour, Tony, Tian, Lei, Lau, Edward, Thomas, Dilip, Itzhaki, Ilanit, Malak, Olfat, Zhang, Joe Z., Qin, Xulei, Wardak, Mirwais, Liu, Yonggang, Chandy, Mark, Black, Katelyn E., Lam, Maggie P.Y., Neofytou, Evgenios, Wu, Joseph C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119193/ https://www.ncbi.nlm.nih.gov/pubmed/33830086 http://dx.doi.org/10.1172/jci.insight.142000 |
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