The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma

No effective systemic treatment is available for patients with unresectable, recurrent, or metastatic mucoepidermoid carcinoma (MEC), the most common salivary gland malignancy. MEC is frequently associated with a t(11;19)(q14-21;p12-13) translocation that creates a CRTC1-MAML2 fusion gene. The CRTC1...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zirong, Ni, Wei, Li, Jian-Liang, Lin, Shuibin, Zhou, Xin, Sun, Yuping, Li, Jennifer W., Leon, Marino E., Hurtado, Maria D., Zolotukhin, Sergei, Liu, Chen, Lu, Jianrong, Griffin, James D., Kaye, Frederic J., Wu, Lizi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119194/
https://www.ncbi.nlm.nih.gov/pubmed/33830080
http://dx.doi.org/10.1172/jci.insight.139497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119194/
https://www.ncbi.nlm.nih.gov/pubmed/33830080
http://dx.doi.org/10.1172/jci.insight.139497

Ejemplares similares