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A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2

Preexisting cross-reactivity to SARS-CoV-2 occurs in the absence of prior viral exposure. However, this has been difficult to quantify at the population level due to a lack of reliably defined seroreactivity thresholds. Using an orthogonal antibody testing approach, we estimated that about 0.6% of n...

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Detalles Bibliográficos
Autores principales: Majdoubi, Abdelilah, Michalski, Christina, O’Connell, Sarah E., Dada, Sarah, Narpala, Sandeep, Gelinas, Jean, Mehta, Disha, Cheung, Claire, Winkler, Dirk F.H., Basappa, Manjula, Liu, Aaron C., Görges, Matthias, Barakauskas, Vilte E., Irvine, Mike, Mehalko, Jennifer, Esposito, Dominic, Sekirov, Inna, Jassem, Agatha N., Goldfarb, David M., Pelech, Steven, Douek, Daniel C., McDermott, Adrian B., Lavoie, Pascal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119195/
https://www.ncbi.nlm.nih.gov/pubmed/33720905
http://dx.doi.org/10.1172/jci.insight.146316