Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell population

Compromised regenerative capacity of lung epithelial cells can lead to cellular senescence, which may precipitate fibrosis. While increased markers of senescence have been reported in idiopathic pulmonary fibrosis (IPF), the origin and identity of these senescent cells remain unclear, and tools to c...

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Detalles Bibliográficos
Autores principales: DePianto, Daryle J., Heiden, Jason A. Vander, Morshead, Katrina B., Sun, Kai-Hui, Modrusan, Zora, Teng, Grace, Wolters, Paul J., Arron, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119199/
https://www.ncbi.nlm.nih.gov/pubmed/33705361
http://dx.doi.org/10.1172/jci.insight.143626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119199/
https://www.ncbi.nlm.nih.gov/pubmed/33705361
http://dx.doi.org/10.1172/jci.insight.143626

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