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Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors

It remains unresolved how retinal pigment epithelial cell metabolism is regulated following immune activation to maintain retinal homeostasis and retinal function. We exposed retinal pigment epithelium (RPE) to several stress signals, particularly Toll-like receptor stimulation, and uncovered an abi...

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Detalles Bibliográficos
Autores principales: Scott, Louis M., Vincent, Emma E., Hudson, Natalie, Neal, Chris, Jones, Nicholas, Lavelle, Ed C., Campbell, Matthew, Halestrap, Andrew P., Dick, Andrew D., Theodoropoulou, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119202/
https://www.ncbi.nlm.nih.gov/pubmed/33884963
http://dx.doi.org/10.1172/jci.insight.129429