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Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

Chronic inflammation and immune dysfunction play a key role in the development of non-AIDS–related comorbidities. The aim of our study was to characterize the functional phenotype of immune cells in people living with HIV (PLHIV). We enrolled a cross-sectional cohort study of PLHIV on stable antiret...

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Detalles Bibliográficos
Autores principales: van der Heijden, Wouter A., Van de Wijer, Lisa, Keramati, Farid, Trypsteen, Wim, Rutsaert, Sofie, ter Horst, Rob, Jaeger, Martin, Koenen, Hans J.P.M., Stunnenberg, Hendrik G., Joosten, Irma, Verweij, Paul E., van Lunzen, Jan, Dinarello, Charles A., Joosten, Leo A.B., Vandekerckhove, Linos, Netea, Mihai G., van der Ven, André J.A.M., de Mast, Quirijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119206/
https://www.ncbi.nlm.nih.gov/pubmed/33630761
http://dx.doi.org/10.1172/jci.insight.145928