Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomics

To unequivocally address their unresolved intimate structures in blood, we scrutinized the size distribution of circulating cell-free DNA (cfDNA) using whole-genome sequencing (WGS) from both double- and single-strand DNA library preparations (DSP and SSP, n = 7) and using quantitative PCR (Q-PCR, n...

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Detalles Bibliográficos
Autores principales: Sanchez, Cynthia, Roch, Benoit, Mazard, Thibault, Blache, Philippe, Dache, Zahra Al Amir, Pastor, Brice, Pisareva, Ekaterina, Tanos, Rita, Thierry, Alain R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119211/
https://www.ncbi.nlm.nih.gov/pubmed/33571170
http://dx.doi.org/10.1172/jci.insight.144561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119211/
https://www.ncbi.nlm.nih.gov/pubmed/33571170
http://dx.doi.org/10.1172/jci.insight.144561

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