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Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) are key intracellular mediators in the signal transduction of many cytokines and growth factors. Common γ chain cytokines and interferon-γ that use the JAK/STAT pathway to induce biological responses have been implicated...

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Detalles Bibliográficos
Autores principales: Dai, Zhenpeng, Chen, James, Chang, Yuqian, Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119218/
https://www.ncbi.nlm.nih.gov/pubmed/33830087
http://dx.doi.org/10.1172/jci.insight.142205