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Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) are key intracellular mediators in the signal transduction of many cytokines and growth factors. Common γ chain cytokines and interferon-γ that use the JAK/STAT pathway to induce biological responses have been implicated...
Autores principales: | Dai, Zhenpeng, Chen, James, Chang, Yuqian, Christiano, Angela M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119218/ https://www.ncbi.nlm.nih.gov/pubmed/33830087 http://dx.doi.org/10.1172/jci.insight.142205 |
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