miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Lung cancer is still the leading cause of death by cancer worldwide despite advances both in its detection and therapy. Multiple oncogenic driver alterations have been discovered, opening the prospective for new potential therapeutic targets. Among them, KRAS mutations represent the most frequent on...

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Detalles Bibliográficos
Autores principales: Palma, Francesco, Affinito, Alessandra, Nuzzo, Silvia, Roscigno, Giuseppina, Scognamiglio, Iolanda, Ingenito, Francesco, Martinez, Lola, Franzese, Monica, Zanfardino, Mario, Soricelli, Andrea, Fiorelli, Alfonso, Condorelli, Gerolama, Quintavalle, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119240/
https://www.ncbi.nlm.nih.gov/pubmed/32948832
http://dx.doi.org/10.1038/s41417-020-00224-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119240/
https://www.ncbi.nlm.nih.gov/pubmed/32948832
http://dx.doi.org/10.1038/s41417-020-00224-1

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