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miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer
Lung cancer is still the leading cause of death by cancer worldwide despite advances both in its detection and therapy. Multiple oncogenic driver alterations have been discovered, opening the prospective for new potential therapeutic targets. Among them, KRAS mutations represent the most frequent on...
Autores principales: | Palma, Francesco, Affinito, Alessandra, Nuzzo, Silvia, Roscigno, Giuseppina, Scognamiglio, Iolanda, Ingenito, Francesco, Martinez, Lola, Franzese, Monica, Zanfardino, Mario, Soricelli, Andrea, Fiorelli, Alfonso, Condorelli, Gerolama, Quintavalle, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119240/ https://www.ncbi.nlm.nih.gov/pubmed/32948832 http://dx.doi.org/10.1038/s41417-020-00224-1 |
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