Ad5/3 is able to avoid neutralization by binding to erythrocytes and lymphocytes

Oncolytic adenoviruses are promising cancer therapeutic agents. Clinical data have shown adenoviruses’ ability to transduce tumors after systemic delivery in human cancer patients, despite antibodies. In the present work, we have focused on the interaction of a chimeric adenovirus Ad5/3 with human l...

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Detalles Bibliográficos
Autores principales: Zafar, Sadia, Quixabeira, Dafne Carolina Alves, Kudling, Tatiana Viktorovna, Cervera-Carrascon, Victor, Santos, Joao Manuel, Grönberg-Vähä-Koskela, Susanna, Zhao, Fang, Aronen, Pasi, Heiniö, Camilla, Havunen, Riikka, Sorsa, Suvi, Kanerva, Anna, Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119244/
https://www.ncbi.nlm.nih.gov/pubmed/32920593
http://dx.doi.org/10.1038/s41417-020-00226-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119244/
https://www.ncbi.nlm.nih.gov/pubmed/32920593
http://dx.doi.org/10.1038/s41417-020-00226-z

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