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Leptin activates Akt in oesophageal cancer cells via multiple atorvastatin-sensitive small GTPases
Obesity is a risk factor for Barrett’s oesophagus and oesophageal adenocarcinoma. Adipose tissue secretes the hormone leptin. Leptin is a growth factor for several cell types, including Barrett’s cells and oesophageal adenocarcinoma cells. Statins are associated with reduced rates of Barrett’s oesop...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119259/ https://www.ncbi.nlm.nih.gov/pubmed/33582946 http://dx.doi.org/10.1007/s11010-021-04067-8 |