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Biochemical and structural insights into Rab12 interactions with RILP and its family members
Alongside its biosynthetic functions, the small GTPase Rab12 negatively regulates mast cell (MC) exocytosis by its interaction with RILP to promote retrograde transport of the MC secretory granules. Given the role of Rab effectors in mediating Rab functions, in this study we used biochemical and in...
Autores principales: | Omar, Jana, Rosenbaum, Efrat, Efergan, Adi, Sneineh, Bayan Abu, Yeheskel, Adva, Maruta, Yuto, Fukuda, Mitsunori, Sagi-Eisenberg, Ronit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119438/ https://www.ncbi.nlm.nih.gov/pubmed/33986343 http://dx.doi.org/10.1038/s41598-021-89394-y |
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