Curbing action potential generation or ATP-synthase leads to a decrease in in-cell pyruvate dehydrogenase activity in rat cerebrum slices

Direct and real-time monitoring of cerebral metabolism exploiting the drastic increase in sensitivity of hyperpolarized (13)C-labeled metabolites holds the potential to report on neural activity via in-cell metabolic indicators. Here, we followed the metabolic consequences of curbing action potentia...

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Detalles Bibliográficos
Autores principales: Grieb, Benjamin, Uppala, Sivaranjan, Sapir, Gal, Shaul, David, Gomori, J. Moshe, Katz-Brull, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119472/
https://www.ncbi.nlm.nih.gov/pubmed/33986346
http://dx.doi.org/10.1038/s41598-021-89534-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119472/
https://www.ncbi.nlm.nih.gov/pubmed/33986346
http://dx.doi.org/10.1038/s41598-021-89534-4

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