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Curbing action potential generation or ATP-synthase leads to a decrease in in-cell pyruvate dehydrogenase activity in rat cerebrum slices
Direct and real-time monitoring of cerebral metabolism exploiting the drastic increase in sensitivity of hyperpolarized (13)C-labeled metabolites holds the potential to report on neural activity via in-cell metabolic indicators. Here, we followed the metabolic consequences of curbing action potentia...
Autores principales: | Grieb, Benjamin, Uppala, Sivaranjan, Sapir, Gal, Shaul, David, Gomori, J. Moshe, Katz-Brull, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119472/ https://www.ncbi.nlm.nih.gov/pubmed/33986346 http://dx.doi.org/10.1038/s41598-021-89534-4 |
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