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The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on [Formula: see text] dynamics
Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a substantial loss of [Formula: see text] -cell mass and alteration of [Formula: see text] -cell function in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. The mechanisms for deficiency in [Fo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119479/ https://www.ncbi.nlm.nih.gov/pubmed/33986325 http://dx.doi.org/10.1038/s41598-021-89333-x |