Low Incidence of Opioid-Induced Respiratory Depression Observed with Oliceridine Regardless of Age or Body Mass Index: Exploratory Analysis from a Phase 3 Open-Label Trial in Postsurgical Pain

INTRODUCTION: Advanced age and obesity are reported to increase the risk of opioid-induced respiratory depression (OIRD). Oliceridine, an intravenous opioid, is a G-protein-biased agonist at the µ-opioid receptor that may provide improved safety. The recent phase 3 ATHENA open-label, multicenter stu...

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Detalles Bibliográficos
Autores principales: Brzezinski, Marek, Hammer, Gregory B., Candiotti, Keith A., Bergese, Sergio D., Pan, Peter H., Bourne, Michael H., Michalsky, Cathy, Wase, Linda, Demitrack, Mark A., Habib, Ashraf S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119589/
https://www.ncbi.nlm.nih.gov/pubmed/33502739
http://dx.doi.org/10.1007/s40122-020-00232-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119589/
https://www.ncbi.nlm.nih.gov/pubmed/33502739
http://dx.doi.org/10.1007/s40122-020-00232-x

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