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Silencing CircHIPK3 Sponges miR-93-5p to Inhibit the Activation of Rac1/PI3K/AKT Pathway and Improves Myocardial Infarction-Induced Cardiac Dysfunction

The ceRNA network involving circular RNAs (circRNAs) is essential in the cardiovascular system. We investigated the underlying ceRNA network involving circHIPK3 in myocardial infarction (MI). After an MI model was established, cardiac function was verified, and myocardial tissue damage in mice with...

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Detalles Bibliográficos
Autores principales: Wu, Yijin, Wu, Min, Yang, Jue, Li, Ying, Peng, Wenying, Wu, Meifen, Yu, Changjiang, Fang, Miaoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119651/
https://www.ncbi.nlm.nih.gov/pubmed/33996942
http://dx.doi.org/10.3389/fcvm.2021.645378