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Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase

As the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic engulfs millions worldwide, the quest for vaccines or drugs against the virus continues. The helicase protein of SARS-CoV-2 represents an attractive target for drug discovery since inhibition of helicase activity can suppre...

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Detalles Bibliográficos
Autores principales: Abidi, Syed Hani, Almansour, Nahlah Makki, Amerzhanov, Daulet, Allemailem, Khaled S., Rafaqat, Wardah, Ibrahim, Mahmoud A. A., la Fleur, Philip, Lukac, Martin, Ali, Syed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119689/
https://www.ncbi.nlm.nih.gov/pubmed/33986405
http://dx.doi.org/10.1038/s41598-021-89724-0