Development of P301S tau seeded organotypic hippocampal slice cultures to study potential therapeutics

Intracellular tau inclusions are a pathological hallmark of Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration and other sporadic neurodegenerative tauopathies. Recent in vitro and in vivo studies have shown that tau aggregates may spread to neighbouring cells and fu...

Descripción completa

Detalles Bibliográficos
Autores principales: McCarthy, James M., Virdee, Jasmeet, Brown, Jessica, Ursu, Daniel, Ahmed, Zeshan, Cavallini, Annalisa, Nuthall, Hugh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119691/
https://www.ncbi.nlm.nih.gov/pubmed/33986302
http://dx.doi.org/10.1038/s41598-021-89230-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119691/
https://www.ncbi.nlm.nih.gov/pubmed/33986302
http://dx.doi.org/10.1038/s41598-021-89230-3

Ejemplares similares