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The landscape and driver potential of site-specific hotspots across cancer genomes

Large sets of whole cancer genomes make it possible to study mutation hotspots genome-wide. Here we detect, categorize, and characterize site-specific hotspots using 2279 whole cancer genomes from the Pan-Cancer Analysis of Whole Genomes project and provide a resource of annotated hotspots genome-wi...

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Detalles Bibliográficos
Autores principales: Juul, Randi Istrup, Nielsen, Morten Muhlig, Juul, Malene, Feuerbach, Lars, Pedersen, Jakob Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119706/
https://www.ncbi.nlm.nih.gov/pubmed/33986299
http://dx.doi.org/10.1038/s41525-021-00197-6