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The landscape and driver potential of site-specific hotspots across cancer genomes
Large sets of whole cancer genomes make it possible to study mutation hotspots genome-wide. Here we detect, categorize, and characterize site-specific hotspots using 2279 whole cancer genomes from the Pan-Cancer Analysis of Whole Genomes project and provide a resource of annotated hotspots genome-wi...
Autores principales: | Juul, Randi Istrup, Nielsen, Morten Muhlig, Juul, Malene, Feuerbach, Lars, Pedersen, Jakob Skou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119706/ https://www.ncbi.nlm.nih.gov/pubmed/33986299 http://dx.doi.org/10.1038/s41525-021-00197-6 |
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