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REVERSE phenotyping—Can the phenotype following constitutive Tph2 gene inactivation in mice be transferred to children and adolescents with and without adhd?

INTRODUCTION: Experimental models of neuropsychiatric disorders, for example, ADHD, are used to mimic specific phenotypic traits of a complex human disorder. However, it remains unresolved to what extent the animal phenotype reflects the specific human trait. The null mutant mouse of the serotonin‐s...

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Detalles Bibliográficos
Autores principales: Akhrif, Atae, Roy, Arunima, Peters, Katharina, Lesch, Klaus‐Peter, Romanos, Marcel, Schmitt‐Böhrer, Angelika, Neufang, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119824/
https://www.ncbi.nlm.nih.gov/pubmed/33523602
http://dx.doi.org/10.1002/brb3.2054