Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2

Camostat, nafamostat, and bromhexine are inhibitors of the transmembrane serine protease TMPRSS2. The inhibition of TMPRSS2 has been shown to prevent the viral infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other viruses. However, while camostat and nafamostat inhibit...

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Detalles Bibliográficos
Autores principales: Sgrignani, Jacopo, Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119889/
https://www.ncbi.nlm.nih.gov/pubmed/33996911
http://dx.doi.org/10.3389/fmolb.2021.666626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119889/
https://www.ncbi.nlm.nih.gov/pubmed/33996911
http://dx.doi.org/10.3389/fmolb.2021.666626

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