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A KLF4/PiHL/EZH2/HMGA2 regulatory axis and its function in promoting oxaliplatin-resistance of colorectal cancer

Long noncoding RNAs (lncRNAs) have emerged as a new class of regulatory molecules implicated in therapeutic resistance, yet the mechanisms underlying lncRNA-mediated oxaliplatin resistance in colorectal cancer (CRC) are poorly understood. In this study, lncRNA P53 inHibiting LncRNA (PiHL) was shown...

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Detalles Bibliográficos
Autores principales: Deng, Xuan, Kong, Fanyang, Li, Si, Jiang, Haoqin, Dong, Liu, Xu, Xiao, Zhang, Xinju, Yuan, Hong, Xu, Ying, Chu, Yimin, Peng, Haixia, Guan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119946/
https://www.ncbi.nlm.nih.gov/pubmed/33986248
http://dx.doi.org/10.1038/s41419-021-03753-1