Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis

Osteoarthritis (OA) is a common articular degenerative disease characterized by loss of cartilage matrix and subchondral bone sclerosis. Kartogenin (KGN) has been reported to improve chondrogenic differentiation of mesenchymal stem cells. However, the therapeutic effect of KGN on OA-induced cartilag...

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Detalles Bibliográficos
Autores principales: Hou, Mingzhuang, Zhang, Yijian, Zhou, Xinfeng, Liu, Tao, Yang, Huilin, Chen, Xi, He, Fan, Zhu, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119954/
https://www.ncbi.nlm.nih.gov/pubmed/33986262
http://dx.doi.org/10.1038/s41419-021-03765-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119954/
https://www.ncbi.nlm.nih.gov/pubmed/33986262
http://dx.doi.org/10.1038/s41419-021-03765-x

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