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Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis
Osteoarthritis (OA) is a common articular degenerative disease characterized by loss of cartilage matrix and subchondral bone sclerosis. Kartogenin (KGN) has been reported to improve chondrogenic differentiation of mesenchymal stem cells. However, the therapeutic effect of KGN on OA-induced cartilag...
Autores principales: | Hou, Mingzhuang, Zhang, Yijian, Zhou, Xinfeng, Liu, Tao, Yang, Huilin, Chen, Xi, He, Fan, Zhu, Xuesong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119954/ https://www.ncbi.nlm.nih.gov/pubmed/33986262 http://dx.doi.org/10.1038/s41419-021-03765-x |
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