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Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma

Renal Cell Carcinoma (RCC) is the most common form of kidney cancer, with clear cell RCC (ccRCC) representing about 85% of all RCC tumors. There are limited curable treatments available for metastatic ccRCC because this disease is unresponsive to conventional targeted systemic pharmacotherapy. Exoso...

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Detalles Bibliográficos
Autores principales: Greenberg, Jacob W., Kim, Hogyoung, Moustafa, Ahmed A., Datta, Amrita, Barata, Pedro C., Boulares, A. Hamid, Abdel-Mageed, Asim B., Krane, Louis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119955/
https://www.ncbi.nlm.nih.gov/pubmed/33986386
http://dx.doi.org/10.1038/s41598-021-89655-w