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Rab11-dependent recycling of calcium channels is mediated by auxiliary subunit α(2)δ-1 but not α(2)δ-3

N-type voltage-gated calcium channels (Ca(V)2.2) are predominantly expressed at presynaptic terminals, and their function is regulated by auxiliary α(2)δ and β subunits. All four mammalian α(2)δ subunits enhance calcium currents through Ca(V)1 and Ca(V)2 channels, and this increase is attributed, in...

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Detalles Bibliográficos
Autores principales: Meyer, James O., Dolphin, Annette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119971/
https://www.ncbi.nlm.nih.gov/pubmed/33986433
http://dx.doi.org/10.1038/s41598-021-89820-1