Enantioselective access to chiral aliphatic amines and alcohols via Ni-catalyzed hydroalkylations

Chiral aliphatic amine and alcohol derivatives are ubiquitous in pharmaceuticals, pesticides, natural products and fine chemicals, yet difficult to access due to the challenge to differentiate between the spatially and electronically similar alkyl groups. Herein, we report a nickel-catalyzed enantio...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Zhang, Jian-Xin, Zhang, Tian-Yi, Meng, Huan, Chen, Bi-Hong, Shu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119980/
https://www.ncbi.nlm.nih.gov/pubmed/33986269
http://dx.doi.org/10.1038/s41467-021-22983-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119980/
https://www.ncbi.nlm.nih.gov/pubmed/33986269
http://dx.doi.org/10.1038/s41467-021-22983-7

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