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Enantioselective access to chiral aliphatic amines and alcohols via Ni-catalyzed hydroalkylations
Chiral aliphatic amine and alcohol derivatives are ubiquitous in pharmaceuticals, pesticides, natural products and fine chemicals, yet difficult to access due to the challenge to differentiate between the spatially and electronically similar alkyl groups. Herein, we report a nickel-catalyzed enantio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119980/ https://www.ncbi.nlm.nih.gov/pubmed/33986269 http://dx.doi.org/10.1038/s41467-021-22983-7 |