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Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis

Although therapies of cancer are advancing, it remains challenging for therapeutics to reach the sites of metastasis, which accounts for majority of cancer associated death. In this study, we have developed a strategy that guides an anti-programmed cell death-ligand 1 (aPDL1) antibody to accumulate...

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Detalles Bibliográficos
Autores principales: Li, Hongjun, Wang, Zejun, Chen, Zhaowei, Ci, Tianyuan, Chen, Guojun, Wen, Di, Li, Ruoxin, Wang, Jinqiang, Meng, Huan, Bryan Bell, R., Gu, Zhifeng, Dotti, Gianpietro, Gu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119987/
https://www.ncbi.nlm.nih.gov/pubmed/33986264
http://dx.doi.org/10.1038/s41467-021-22674-3