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Evaluation of tradipitant, a selective NK1 antagonist, on response to oxycodone in humans

RATIONALE: Preclinical studies demonstrate that the NK1 receptor is involved in opioid reinforcement and withdrawal expression. Few studies have examined the impact of treatment with NK1 antagonists on opioid response in humans. OBJECTIVE: To explore the potential for a selective NK1 antagonist, tra...

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Detalles Bibliográficos
Autores principales: Coe, Marion A., Lofwall, Michelle R., Vessels, Victoria, Nuzzo, Paul A., Walsh, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120018/
https://www.ncbi.nlm.nih.gov/pubmed/33988725
http://dx.doi.org/10.1007/s00213-021-05814-x