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Pitfalls of Commonly Used Ischemic and Dementia Models Due to Early Seizure by Carotid Ligation

While the bilateral common carotid artery (CCA) ligation model is widely used in cerebrovascular disease and dementia studies, it can frequently cause seizures. We examined the validity of seizure as an experimental model of ischemia. Eight-week-old male Wistar and Sprague-Dawley (SD) rats were impl...

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Detalles Bibliográficos
Autores principales: HIRANO, Tsukasa, MIKAMI, Takeshi, YAMADA, Shoto, NAGAHAMA, Hiroshi, ENATSU, Rei, OOKAWA, Satoshi, AKIYAMA, Yukinori, MIKUNI, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120100/
https://www.ncbi.nlm.nih.gov/pubmed/33790129
http://dx.doi.org/10.2176/nmc.oa.2020-0365