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Pitfalls of Commonly Used Ischemic and Dementia Models Due to Early Seizure by Carotid Ligation
While the bilateral common carotid artery (CCA) ligation model is widely used in cerebrovascular disease and dementia studies, it can frequently cause seizures. We examined the validity of seizure as an experimental model of ischemia. Eight-week-old male Wistar and Sprague-Dawley (SD) rats were impl...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japan Neurosurgical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120100/ https://www.ncbi.nlm.nih.gov/pubmed/33790129 http://dx.doi.org/10.2176/nmc.oa.2020-0365 |