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A Multimodal Imaging Approach Demonstrates Reduced Midbrain Functional Network Connectivity Is Associated With Freezing of Gait in Parkinson's Disease

Background: The pathophysiological mechanisms underlying freezing of gait (FOG) are poorly defined. MRI studies in FOG showed a distinct pattern of cortical atrophy and decreased functional connectivity (FC) within motor and cognitive networks. Furthermore, reduced rs-FC within midbrain, frontal, an...

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Detalles Bibliográficos
Autores principales: Droby, Amgad, Pelosin, Elisa, Putzolu, Martina, Bommarito, Giulia, Marchese, Roberta, Mazzella, Luca, Avanzino, Laura, Inglese, Matilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120105/
https://www.ncbi.nlm.nih.gov/pubmed/33995237
http://dx.doi.org/10.3389/fneur.2021.583593