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Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells

Facioscapulohumeral muscular dystrophy (FSHD) is an inherited muscle disease caused by misexpression of the DUX4 gene in skeletal muscle. DUX4 is a transcription factor, which is normally expressed in the cleavage-stage embryo and regulates gene expression involved in early embryonic development. Re...

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Detalles Bibliográficos
Autores principales:	Mitsuhashi, Satomi, Nakagawa, So, Sasaki-Honda, Mitsuru, Sakurai, Hidetoshi, Frith, Martin C, Mitsuhashi, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120133/ https://www.ncbi.nlm.nih.gov/pubmed/33693705 http://dx.doi.org/10.1093/hmg/ddab063

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