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Universal Architectural Concepts Underlying Protein Folding Patterns

What is the architectural “basis set” of the observed universe of protein structures? Using information-theoretic inference, we answer this question with a dictionary of 1,493 substructures—called concepts—typically at a subdomain level, based on an unbiased subset of known protein structures. Each...

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Detalles Bibliográficos
Autores principales: Konagurthu, Arun S., Subramanian, Ramanan, Allison, Lloyd, Abramson, David, Stuckey, Peter J., Garcia de la Banda, Maria, Lesk, Arthur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120156/
https://www.ncbi.nlm.nih.gov/pubmed/33996891
http://dx.doi.org/10.3389/fmolb.2020.612920