Structure Activity Relationship of N-Substituted Phenyldihydropyrazolones Against Trypanosoma cruzi Amastigotes

Current drugs for Chagas disease have long treatment regimens with occurrence of adverse drug effects leading to poor treatment compliance. Novel and efficacious medications are therefore highly needed. We previously reported on the discovery of NPD-0227 (2-isopropyl-5-(4-methoxy-3-(pyridin-3-yl)phe...

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Detalles Bibliográficos
Autores principales: Sijm, Maarten, Maes, Louis, de Esch, Iwan J. P., Caljon, Guy, Sterk, Geert Jan, Leurs, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120161/
https://www.ncbi.nlm.nih.gov/pubmed/33996737
http://dx.doi.org/10.3389/fchem.2021.608438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120161/
https://www.ncbi.nlm.nih.gov/pubmed/33996737
http://dx.doi.org/10.3389/fchem.2021.608438

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