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Acidic extracellular pH induces autophagy to promote anoikis resistance of hepatocellular carcinoma cells via downregulation of miR-3663-3p

Metastasis is the major reason for poor prognosis and high fatality in hepatocellular carcinoma (HCC). Due to the “Warburg effect”, an acidic tumor microenvironment (TME) exists in solid tumors and plays a critical role in cancer metastasis. Thus, clarifying the mechanism underlying the acidic TME i...

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Detalles Bibliográficos
Autores principales: Wang, Siying, Lv, Yuanyuan, Zhou, Yangyang, Ling, Jing, Wang, Hui, Gu, Dishui, Wang, Cun, Qin, Wenxin, Zheng, Xingling, Jin, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120191/
https://www.ncbi.nlm.nih.gov/pubmed/33995620
http://dx.doi.org/10.7150/jca.51849