Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS

The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of sodium iodide symporter (NIS), diminished targeting of NIS to the cell membrane, or both, thereby decreasing the efficacy of...

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Detalles Bibliográficos
Autores principales: Oh, Ji Min, Ahn, Byeong-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120202/
https://www.ncbi.nlm.nih.gov/pubmed/33995657
http://dx.doi.org/10.7150/thno.57689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120202/
https://www.ncbi.nlm.nih.gov/pubmed/33995657
http://dx.doi.org/10.7150/thno.57689

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