Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease

Purpose: The increase in butyrylcholinesterase (BChE) activity in the brain of Alzheimer disease (AD) patients and animal models of AD position this enzyme as a potential biomarker of the disease. However, the information on the ability of BChE to serve as AD biomarker is contradicting, also due to...

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Detalles Bibliográficos
Autores principales: Rejc, Luka, Gómez-Vallejo, Vanessa, Joya, Ana, Moreno, Oscar, Egimendia, Ander, Castellnou, Pilar, Ríos-Anglada, Xabier, Cossío, Unai, Baz, Zuriñe, Passannante, Rossana, Tobalina-Larrea, Ignacio, Ramos-Cabrer, Pedro, Giralt, Albert, Sastre, Magdalena, Capetillo-Zarate, Estibaliz, Košak, Urban, Knez, Damijan, Gobec, Stanislav, Marder, Mariel, Martin, Abraham, Llop, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120209/
https://www.ncbi.nlm.nih.gov/pubmed/33995675
http://dx.doi.org/10.7150/thno.54589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120209/
https://www.ncbi.nlm.nih.gov/pubmed/33995675
http://dx.doi.org/10.7150/thno.54589

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