DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells

Rationale: Dysregulation of the PI3K/AKT/mTOR pathway occurs frequently in cancers, providing an attractive therapeutic target for anticancer treatments. DEPTOR plays essential roles in regulation of cell proliferation and survival by directly modulating mTOR activity. However, whether DEPTOR regula...

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Detalles Bibliográficos
Autores principales: Bi, Yanli, Chen, Xiaoyu, Wei, Bajin, Wang, Linchen, Gong, Longyuan, Li, Haomin, Xiong, Xiufang, Zhao, Yongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120212/
https://www.ncbi.nlm.nih.gov/pubmed/33995662
http://dx.doi.org/10.7150/thno.51286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120212/
https://www.ncbi.nlm.nih.gov/pubmed/33995662
http://dx.doi.org/10.7150/thno.51286

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