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EGFR inhibition blocks cancer stem cell clustering and lung metastasis of triple negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and metastatic breast cancer subtypes lacking targeted therapy. Our recent work demonstrated that circulating tumor cell (CTC) clusters and polyclonal metastasis of TNBC are driven by aggregation of CD44(+) cancer stem cells (CSC) an...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120216/ https://www.ncbi.nlm.nih.gov/pubmed/33995681 http://dx.doi.org/10.7150/thno.57706 |