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Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization

Myocardial fibrosis is closely related to high morbidity and mortality. In Inner Mongolia, Gentianella amarella subsp. acuta (Michx.) J.M.Gillett (G. acuta) is a kind of tea used to prevent cardiovascular diseases. Bellidifolin (BEL) is an active xanthone molecule from G. acuta that protects against...

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Detalles Bibliográficos
Autores principales: Yang, Hong-Xia, Sun, Jia-Huan, Yao, Ting-Ting, Li, Yuan, Xu, Geng-Rui, Zhang, Chuang, Liu, Xing-Chao, Zhou, Wei-Wei, Song, Qiu-Hang, Zhang, Yue, Li, Ai-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120298/
https://www.ncbi.nlm.nih.gov/pubmed/33995055
http://dx.doi.org/10.3389/fphar.2021.644886