Crocetin and Its Glycoside Crocin, Two Bioactive Constituents From Crocus sativus L. (Saffron), Differentially Inhibit Angiogenesis by Inhibiting Endothelial Cytoskeleton Organization and Cell Migration Through VEGFR2/SRC/FAK and VEGFR2/MEK/ERK Signaling Pathways

Crocetin and crocin are two important carotenoids isolated from saffron (Crocus sativus L.), which have been used as natural biomedicines with beneficial effects for improving the suboptimal health status associated with abnormal angiogenesis. However, the anti-angiogenic effects and underlying mech...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Kam, Hio-Tong, Chen, Yan, Gong, Guiyi, Hoi, Maggie Pui-Man, Skalicka-Woźniak, Krystyna, Dias, Alberto Carlos Pires, Lee, Simon Ming-Yuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120304/
https://www.ncbi.nlm.nih.gov/pubmed/33995106
http://dx.doi.org/10.3389/fphar.2021.675359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120304/
https://www.ncbi.nlm.nih.gov/pubmed/33995106
http://dx.doi.org/10.3389/fphar.2021.675359

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