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Effect of oxymatrine on liver gluconeogenesis is associated with the regulation of PEPCK and G6Pase expression and AKT phosphorylation

An increase in liver gluconeogenesis is an important pathological phenomenon in type 2 diabetes mellitus (T2DM) and oxymatrine is an effective natural drug used for T2DM treatment. The present study aimed to explore the effect of oxymatrine on gluconeogenesis and elucidate the underlying mechanism....

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Detalles Bibliográficos
Autores principales: Zhu, Yu-Xian, Hu, Hai-Qing, Zuo, Mei-Ling, Mao, Li, Song, Gui-Lin, Li, Tao-Ming, Dong, Li-Chen, Yang, Zhong-Bao, Ali Sheikh, Md Sayed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120346/
https://www.ncbi.nlm.nih.gov/pubmed/34007449
http://dx.doi.org/10.3892/br.2021.1432