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Evaluation of phosphodiesterase 9A as a novel biomarker in heart failure with preserved ejection fraction

AIMS: Murine models implicate phosphodiesterase 9A (PDE9A) as a nitric oxide‐independent regulator of cyclic guanosine monophosphate and promising novel therapeutic target in heart failure (HF) with preserved ejection fraction (HFpEF). This study describes PDE9A expression in endomyocardial biopsies...

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Detalles Bibliográficos
Autores principales: Besler, Christian, Rommel, Karl‐Philipp, Kresoja, Karl‐Patrik, Mörbitz, Justus, Kirsten, Holger, Scholz, Markus, Klingel, Karin, Thiery, Joachim, Burkhardt, Ralph, Büttner, Petra, Adams, Volker, Thiele, Holger, Lurz, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120363/
https://www.ncbi.nlm.nih.gov/pubmed/33787083
http://dx.doi.org/10.1002/ehf2.13327